The papers include correspondence, photographs, postcards, shorthand notes, travel documents, and bound material.

The correspondence in this collection is divided into two subsets. The first includes items received by James F. Byrnes between the years 1934-1958. Among these items are letters from political figures such as President Franklin D. Roosevelt, Eleanor Roosevelt, and Winston Churchill. In addition, there are letters from notable Hollywood figures such as Spencer Tracy and Clark Gable. The second set of correspondence contains material that Cassie Connor either sent or received. These include received items from relatives stationed overseas during World War II as well as letters from Bernard Baruch.

There are 128 photographs that depict Byrnes, Connor, and members of various U.S. delegations and political figures that accompanied them on diplomatic missions such as Potsdam in 1945 and the Paris Peace Conference in 1946.

Of note are six postcards addressed to Hermann Göring from German well-wishers concerning the birth of his daughter Edda in 1938. These were found in the book Hermann Göring Redun und Aufsatze from this collection. It is unknown how Connor came into possession of these particular materials.

Included in this collection are three pages of shorthand notes by Byrnes that were taken on July 4, 1946 [it should be noted that Byrnes used Pittman shorthand].

Connor’s travel documents include a certificate of vaccination (1966), a diary (years 1959, 1961, and 1966), three passports, and an undated travel itinerary.

There are three bound items within this collection. The first is a March 1947 edition of South Carolina Magazine which features an article entitled "Mister Justice: James F. Byrnes of South Carolina." The second and third items are related to the formation of the United Nations. One contains interim arrangements agreed upon in 1945 while the other is a bound copy of the charter itself.