The records of this series contain material primarily from the 1960's and the 1970's which clearly reflects the functions of the administrative assistant. The material generally pertains to office operations and policies, patronage, political campaigns, and some miscellaneous functions. These materials include letters, memoranda, reports, articles from magazines and newspapers, and some speeches. The series is divided into four subseries: Subject File, Becki Edwards Files, Linda Guell Files, and Interns and Pages.

The "Subject Files" subseries (Subseries A, 1936-1989; 9.0 cu. ft.) contains the materials covering the office operations, patronage, political campaigns, and various other topics. This series is arranged alphabetically by folder title and chronologically within each folder. There is information on operational policies and office procedures, descriptions of the office positions, and lists of the senator's staff. In addition, there is some information on the rules, regulations and procedures of the United States Senate. Materials from some committees are also included. Information can be found on some cases and patronage, such as judgeships and U.S. Marshalls. There is correspondence and other materials concerning the Democratic Party, and letters congratulating Thurmond on winning the 1972 Election. Furthermore, there are records on the political campaigns of 1960, 1964 and 1972. This subseries has some White House correspondence, letters on the Vietnam War, and lists of the members of the Thurmond family.

The Subject Files subseries also contains information on the Southern Manifesto and on postal matters in South Carolina during the 1950's. In addition, there are records on the Freedoms Foundation, school desegregation, South Carolina school districts, textiles, and the United Nations Children's Fund (UNICEF).

The Becki Edwards Files subseries (Subseries B, 1975-1978; 9.0 cu. ft.) has the material used by Becki Edwards, a secretary who worked on Senator Thurmond's staff from 1976-1980 and assisted the administrative assistant. Most of the records in this subseries concerns general correspondence and wedding invitations. However, there is some material on the 1978 campaign and a biography of Nancy Moore Thurmond.

The Linda Guell Files subseries (Subseries C, 1967-1978; 1.125 cu. ft.) contains the records of another secretary who assisted the administrative assistant and worked the years 1967-1969, 1974, and 1976. The majority of the records in this subseries is correspondence. Some of the correspondence concerns the elections of 1972 and 1978. There are some finanical statements and contributions for the 1972 campaign.

The Interns and Pages subseries (Subseries D, 1966-1988; .675 cu. ft.) has the material pertaining to the interns and pages. Information on the intern programs and their schedules can be found in this subseries. In addition, there are essays written by the interns. There are lists of the interns and pages.

Important South Carolinians in this series include Walter J. Brown ; United States Senators Olin D. Johnston and Ernest F. Hollings; United States Congress-man William J. Bryan Dorn ; Dean Walter Cox of Clemson University; and Judge Clement F. Haynesworth. Other important individuals include President Lyndon B. Johnson; United States Senator Herman Talmadge; and Adlai Stevenson.