The Jean Crouch Thurmond series primarily covers the period 1947-1960, from her courtship with Governor Thurmond to her death. The records are divided into five subseries: Wedding Correspondence, General Correspondence, General Subject File, Illness/Sympathy, and three oversize volumes of Scrapbooks. The Wedding Correspondence (Subseries A, 1947; .75 cu. ft.) is arranged alphabetically. This subseries contains correspondence concerning the pending Thurmond-Crouch marriage and open house invitations following their honeymoon. All of the responses were handled by the governor's office staff.

The General Correspondence subseries (Subseries B, 1947-1959; .33 cu. ft.) is arranged alphabetically and then chronologically within each letter of the alphabet. This subseries contains correspondence between Jean and Strom during their courtship and marriage. In addition, there are letters from Jean's mother and sister.

The General Subject File subseries (Subseries C, 1947-1962; 2 cu. ft.) is arranged alphabetically by folder title and then chronologically within each folder. This subseries deals with the various activities of Jean Thurmond during the early senatorial years. However, there are newspaper clippings covering the period from the Thurmonds' engagement to Mrs. Thurmond's death, and information about the families' lineages. Other items of interest include a guestbook from the wedding, a copy of the marriage license, and some material connected to Alberta Lachicotte's Rebel Senator.

The Illness/Sympathy subseries (Subseries D, 1959-1960; 8.25 cu. ft.) is divided into two sub-subseries: General Correspondence and Subject File. The General Correspondence is divided into two areas: illness and sympathy. Each section is arranged alphabetically by folder title and then alphabetically within each folder. This large sub-subseries contains correspondence relating to Jean Thurmond's illness and death. There are letters, cards, and telegrams from people inside and outside of South Carolina which were basically answered by the Senator's office staff.

The second sub-subseries of the Illness/Sympathy subseries, the Subject File, is arranged alphabetically by folder title and then generally alphabetically within each folder. This sub-subseries deals with other matters connected to Jean Thurmond's illness and death, including the sending of flowers and gifts, as well as donations and contributions to various organizations. In addition, there is a copy of the death certificate, two medical reports, two funeral registers, and an album paying tribute to the late Jean Thurmond.

The Scrapbooks subseries (Subseries E, 1943-1960; 2 reels microfilm) are roughly arranged in chronological order. These scrapbooks contain newspaper clippings and other material covering Jean Thurmond's life. Many of the clippings are duplicates of those found in Strom Thurmond's scrapbooks.

Important correspondents in this series from South Carolina include James F. Byrnes, Harry Dent, William Jennings Bryan Dorn, Robert C. Edwards, and George Bell Timmerman, Jr. Other important correspondents include Robert C. Byrd, Thomas E. Dewey, Dwight D. Eisenhower, J. Edgar Hoover, Hubert H. Humphrey, Lyndon B. Johnson, John F. Kennedy, Robert Kennedy, Richard M. Nixon, Richard B. Russell and Herman Talmadge.